Do NOT use Rizact if:

you are allergic to any ingredient in rizatriptan; you have a history of ischemic heart disease (eg, angina, a heart attack), coronary artery disease (CAD), other moderate to severe heart problems, brain blood vessel disease (eg, a stroke, a transient ischemic attack), or other blood vessel disease (eg, Raynaud syndrome, ischemic bowel disease); you have uncontrolled high blood pressure; you have certain types of migraine headache (hemiplegic, basilar); you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the past 14 days; you have used certain other migraine medicines within the past 24 hours.

Some medical conditions may interact with rizatriptan. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

-if you are pregnant, planning to become pregnant, or are breast-feeding

-if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

-if you have allergies to medicines, foods, or other substances

-if you have a history of diabetes, kidney or liver problems, heart problems, chest pain, shortness of breath, high blood cholesterol, or high blood pressure

-if you are on dialysis

Check with your doctor if any of these most COMMON side effects persist or become bothersome: Dizziness; drowsiness; dry mouth; fatigue; nausea; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody diarrhea; burning, numbness, or tingling of the hands or feet; chest heaviness; chest, neck, or jaw pain, tightness, or pressure; decreased coordination; excessive sweating; fainting; fast, slow, or irregular heartbeat; fever; hallucinations; mental or mood changes (eg, agitation); muscle spasms; seizure; severe nausea, vomiting, or diarrhea; severe or persistent headache or dizziness; shortness of breath; stomach pain; symptoms of stroke (eg, confusion, one-sided weakness, slurred speech); tremor; unusual weakness; very cold or blue fingers or toes; vision changes or loss of vision.